Detalhe da pesquisa
1.
Deep mutational learning predicts ACE2 binding and antibody escape to combinatorial mutations in the SARS-CoV-2 receptor-binding domain.
Cell
; 185(21): 4008-4022.e14, 2022 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36150393
2.
Soluble wild-type ACE2 molecules inhibit newer SARS-CoV-2 variants and are a potential antiviral strategy to mitigate disease severity in COVID-19.
Clin Exp Immunol
; 214(3): 289-295, 2023 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37565297
3.
High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis.
Nucleic Acids Res
; 46(14): 7436-7449, 2018 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29931269
4.
High-resolution antibody dynamics of vaccine-induced immune responses.
Proc Natl Acad Sci U S A
; 111(13): 4928-33, 2014 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24639495
5.
Antibody Fc engineering improves frequency and promotes kinetic boosting of serial killing mediated by NK cells.
Blood
; 124(22): 3241-9, 2014 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25232058
6.
Surveying the Delivery Methods of CRISPR/Cas9 for ex vivo Mammalian Cell Engineering.
Chimia (Aarau)
; 70(6): 439-42, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27363374
7.
Mechanisms of host manipulation by Neisseria gonorrhoeae.
Front Microbiol
; 14: 1119834, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36819065
8.
Red edge excitation shift spectroscopy is highly sensitive to tryptophan composition.
J R Soc Interface
; 20(208): 20230337, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37935360
9.
Constant domain polymorphisms influence monoclonal antibody stability and dynamics.
Protein Sci
; 32(3): e4589, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36759959
10.
Immunogenic fusion proteins induce neutralizing SARS-CoV-2 antibodies in the serum and milk of sheep.
Biotechnol Rep (Amst)
; 38: e00791, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-36915646
11.
Impact of prepartum administration of a vaccine against infectious calf diarrhea on nonspecific colostral immunoglobulin concentrations of dairy cows.
J Anim Sci
; 100(8)2022 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35678245
12.
Deep mutational scanning for therapeutic antibody engineering.
Trends Pharmacol Sci
; 43(2): 123-135, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34895944
13.
Beyond Allotypes: The Influence of Allelic Diversity in Antibody Constant Domains.
Front Immunol
; 11: 2016, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32973808
14.
Molecular Design, Optimization, and Genomic Integration of Chimeric B Cell Receptors in Murine B Cells.
Front Immunol
; 10: 2630, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31798579
15.
Reprogramming MHC specificity by CRISPR-Cas9-assisted cassette exchange.
Sci Rep
; 7: 45775, 2017 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28374766
16.
Immunogenomic engineering of a plug-and-(dis)play hybridoma platform.
Nat Commun
; 7: 12535, 2016 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27531490
17.
IgGA: a "cross-isotype" engineered human Fc antibody domain that displays both IgG-like and IgA-like effector functions.
Chem Biol
; 21(12): 1603-9, 2014 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25500223
18.
Effective phagocytosis of low Her2 tumor cell lines with engineered, aglycosylated IgG displaying high FcγRIIa affinity and selectivity.
ACS Chem Biol
; 8(2): 368-75, 2013 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23030766
19.
Bypassing glycosylation: engineering aglycosylated full-length IgG antibodies for human therapy.
Curr Opin Biotechnol
; 22(6): 858-67, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21420850